The Ubiquitin and Ubiquitin-like Conjugation Database (UUCD) is a comprehensive database, in which we have collected and sorted all experimentally demonstrated enzymes, particularly ubiquitin ligases, from more than 30,000 articles by literature retrieval and predicted 57,015 potential enzymes in 70 sequenced proteomes. To date, UUCD 1.0 has contained E1s (Ubiquitin-activating enzymes), E2s (ubiquitin-conjugating enzymes or ubiquitin-carrier enzymes), E3s (ubiquitin ligases) and DUBs (Deubiquitinating enzymes) of ubiquitination and ubiquitin-like modifications.

    UUCD 1.0 classifies all the animal, fungus and plant enzymes into 30 families. Besides, UUCD 1.0 provides annotation information for all the E1s, E2s, E3s and DUBs in the database, which includes the basic information, functional domain, Genbank accession, GO annotation, orthologs, KEGG, Interpro, Pfam, SMART and cross links to other databases. Users can browse the database:(i) By species; (ii) By classifications

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